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EVs preparation To eliminate cellular remnants and large-scale vesicles, plasma samples were thawed on ice, followed by centrifugation at 1,500 g at 4 C for 10 min

Tranexamic Acid This is a weak tyrosinase inhibitor, but really has effects on plasmin

Long-term consistency is key to maintaining progress

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Single group studies showed favourable OS and PFS compared to historical controls [82, 111, 129] and institutional averages [110]